Anti-TRAPPC14 antibody (STJA0009214)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human C7orf43
General Information
| Short Description | Rabbit polyclonal anti-Trafficking protein particle complex subunit 14 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TRAPPC14 |
| Gene ID | 55262 |
| Uniprot ID | TPC14_HUMAN |
| Immunogen | Synthesized peptide derived from human C7orf43 |
| Specificity | This antibody detects endogenous levels of C7orf43 at Human, Mouse |
Additional Info
| Function | Specific subunit of the TRAPP (transport protein particle) II complex, a highly conserved vesicle tethering complex that functions in late Golgi trafficking as a membrane tether. TRAPP II complex also has GEF activity toward RAB1A. TRAPPC14 is dispensable for TRAPPII complex integrity but mediates RAB3IP preciliary vesicle trafficking to the mother centriole during ciliogenesis. Modulates YAP1 activity as transcriptional regulator. |
| Protein Name | Trafficking Protein Particle Complex Subunit 14Microtubule-Associated Protein 11 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonSpindleVesicleMidbodyDuring MitosisPrecedes Alpha-Tubulin In Gap Formation Of Cell Abscission At The Midbody And Is Co-Localized With Plk1 At The Edges Of Microtubules Extensions Of Daughter Cells Post Cytokinesis AbscissionColocalizes With Rab3ip On Preciliary Vesicles |
| Alternative Antibody Names | Anti-Trafficking Protein Particle Complex Subunit 14 antibodyAnti-Microtubule-Associated Protein 11 antibodyAnti-TRAPPC14 antibodyAnti-C7orf43 antibodyAnti-MAP11 antibody |
Information sourced from Uniprot.org