• Western blot analysis of extracts of various cell lines, using TBL3 antibody (STJ112083) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.

Anti-TBL3 antibody (579-808) (STJ112083)

SKU:
STJ112083

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-TBL3 (579-808) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:1000-1:4000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TBL3
Gene ID: 10607
Uniprot ID: TBL3_HUMAN
Immunogen Region: 579-808
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 579-808 of human TBL3 (NP_006444.2).
Immunogen Sequence: LSSGSDGLVKLWTIKNNECV RTLDAHEDKVWGLHCSRLDD HALTGASDSRVILWKDVTEA EQAEEQARQEEQVVRQQELD NLLHEKRYLRALGLAISLDR PHTVLTVIQAIRRDPEACEK LEATMLRLRRDQKEALLRFC VTWNTNSRHCHEAQAVLGVL LRREAPEELLAYEGVRAALE ALLPYTERHFQRLSRTLQAA AFLDFLWHNMKLPVPAAAPT PWETHKGALP
Function Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome.
Protein Name Transducin Beta-Like Protein 3
Wd Repeat-Containing Protein Sazd
Database Links Reactome: R-HSA-6790901
Reactome: R-HSA-6791226
Cellular Localisation Nucleus
Nucleolus
Alternative Antibody Names Anti-Transducin Beta-Like Protein 3 antibody
Anti-Wd Repeat-Containing Protein Sazd antibody
Anti-TBL3 antibody
Anti-SAZD antibody

Information sourced from Uniprot.org

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