Anti-SV40 T Antigen antibody [R08-7D4] (STJA0035374)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of SV40 T-antigen
STJA0035374
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General Information

Short DescriptionRabbit monoclonal anti-SV40 T antigen for use in WB, ICC, IF and IP in All samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ICC/IF/IP
HostRabbit
ReactivityAll
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDR08-7D4
IsotypeIgG
ConjugationUnconjugated
Concentration0.3 mg/mL
PurificationAffinity Purified
Dilution RangeWB 1:500-1:1000
IF 1:50-1:200
IP 1:20
Formulation50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage InstructionStore at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.

Target Information

ImmunogenA synthetic peptide of SV40 T-antigen

Additional Info

Background Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA. Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.

Information sourced from Uniprot.org

Citations

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