Anti-SORBS1 antibody (STJA0007466)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human SORBS1
General Information
| Short Description | Rabbit polyclonal anti-Sorbin and SH3 domain-containing protein 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SORBS1 |
| Gene ID | 10580 |
| Uniprot ID | SRBS1_HUMAN |
| Immunogen | Synthesized peptide derived from human SORBS1 |
| Specificity | This antibody detects endogenous levels of SORBS1 at Human, Mouse, Rat |
Additional Info
| Post Translational Modifications | O-glycosylated. |
| Function | Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions. |
| Protein Name | Sorbin And Sh3 Domain-Containing Protein 1PonsinSh3 Domain Protein 5Sh3p12C-Cbl-Associated ProteinCap |
| Database Links | Reactome: R-HSA-445355 |
| Cellular Localisation | Cell JunctionAdherens JunctionCell MembraneCytoplasmCytoskeletonFocal AdhesionNucleusNucleus MatrixColocalizes With The Ten-1 Icd Form Of Tenm1 In The NucleusColocalizes With Actin Stress FibersAlso Detected At The Plasma Membrane And In Neuronal Intranuclear InclusionsColocalized With Pxn At Focal Adhesions During Myogenic Differentiation |
| Alternative Antibody Names | Anti-Sorbin And Sh3 Domain-Containing Protein 1 antibodyAnti-Ponsin antibodyAnti-Sh3 Domain Protein 5 antibodyAnti-Sh3p12 antibodyAnti-C-Cbl-Associated Protein antibodyAnti-Cap antibodyAnti-SORBS1 antibodyAnti-KIAA0894 antibodyAnti-KIAA1296 antibodyAnti-SH3D5 antibody |
Information sourced from Uniprot.org