| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-SLC25A13 (1-300) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
SLC25A13 |
| Gene ID: |
10165 |
| Uniprot ID: |
S2513_HUMAN |
| Immunogen Region: |
1-300 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SLC25A13 (NP_001153682.1). |
| Immunogen Sequence: |
MAAAKVALTKRADPAELRTI FLKYASIEKNGEFFMSPNDF VTRYLNIFGESQPNPKTVEL LSGVVDQTKDGLISFQEFVA FESVLCAPDALFMVAFQLFD KAGKGEVTFEDVKQVFGQTT IHQHIPFNWDSEFVQLHFGK ERKRHLTYAEFTQFLLEIQL EHAKQAFVQRDNARTGRVTA IDFRDIMVTIRPHVLTPFVE ECLVAAAGGTTSHQVSFSYF NGFNSLLNNMELIRKIYST |
| Tissue Specificity | High levels in liver and low levels in kidney, pancreas, placenta, heart and brain. |
| Function | Mitochondrial electrogenic aspartate/glutamate antiporter that favors efflux of aspartate and entry of glutamate and proton within the mitochondria as part of the malate-aspartate shuttle. Also mediates the uptake of L-cysteinesulfinate by mitochondria in exchange of L-glutamate and proton. Can also exchange L-cysteinesulfinate with aspartate in their anionic form without any proton translocation. |
| Protein Name | Electrogenic Aspartate/Glutamate Antiporter Slc25a13 - MitochondrialCalcium-Binding Mitochondrial Carrier Protein Aralar2Aralar-Related Gene 2Aralar2CitrinMitochondrial Aspartate Glutamate Carrier 2Solute Carrier Family 25 Member 13 |
| Database Links | Reactome: R-HSA-1268020Reactome: R-HSA-70263Reactome: R-HSA-8963693 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Electrogenic Aspartate/Glutamate Antiporter Slc25a13 - Mitochondrial antibodyAnti-Calcium-Binding Mitochondrial Carrier Protein Aralar2 antibodyAnti-Aralar-Related Gene 2 antibodyAnti-Aralar2 antibodyAnti-Citrin antibodyAnti-Mitochondrial Aspartate Glutamate Carrier 2 antibodyAnti-Solute Carrier Family 25 Member 13 antibodyAnti-SLC25A13 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and BUB1 knockout (KO) HeLa cells, using [KO Validated] BUB1 Rabbit polyclonal antibody (STJ11100026) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89098/357557/STJ11100026_1__69013.1713121681.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and BUB1 knockout (KO) HeLa cells, using [KO Validated] BUB1 Rabbit polyclonal antibody (STJ11100026) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1min.")
