• Immunofluorescence analysis of U2OS cells using SLC25A13 antibody (STJ114431). Blue: DAPI for nuclear staining.
  • Immunohistochemistry of paraffin-embedded human lung cancer using SLC25A13 antibody (STJ114431) at dilution of 1:100 (40x lens).
  • Immunohistochemistry of paraffin-embedded human colon carcinoma using SLC25A13 antibody (STJ114431) at dilution of 1:100 (40x lens).
  • Western blot analysis of extracts of various cell lines, using SLC25A13 antibody (STJ114431) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.

Anti-SLC25A13 antibody (STJ114431)

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STJ114431
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Host: Rabbit
Applications: WB, IHC, IF
Reactivity: Human
Short Description: Rabbit polyclonal primary antibody against SLC25A13.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Storage Instruction: Store at-20°C. Avoid freeze/thaw cycles.
Isotype: IgG
Dilution Range: WB: 1:500-1:2000
IHC: 1:50-1:200
IF: 1:50-1:200
Uniprot ID: CMC2_HUMAN
Gene ID: 10165
Gene Symbol: SLC25A13
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SLC25A13 (NP_001153682.1).
Background This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca (2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
Tissue Specificity High levels in liver and low levels in kidney, pancreas, placenta, heart and brain.
Function Mitochondrial and calcium-binding carrier that catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.
Database Links Reactome: R-HSA-1268020
Cellular Localisation Mitochondrion Inner Membrane
Multi-Pass Membrane Protein
Protein Name Calcium-Binding Mitochondrial Carrier Protein Aralar2
Citrin
Mitochondrial Aspartate Glutamate Carrier 2
Solute Carrier Family 25 Member 13
Alternative Names Anti-Calcium-Binding Mitochondrial Carrier Protein Aralar2 antibody
Anti-Citrin antibody
Anti-Mitochondrial Aspartate Glutamate Carrier 2 antibody
Anti-Solute Carrier Family 25 Member 13 antibody
Anti-SLC25A13 antibody
Anti-ARALAR2 antibody

Information sourced from uniprot.org

6 months standard