• Western blot analysis of extracts of mouse pancreas, using SFRP2 antibody (STJ114825) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90s.

Anti-SFRP2 antibody (STJ114825)

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Host: Rabbit
Applications: WB
Reactivity: Mouse
Short Description: Rabbit polyclonal primary antibody against SFRP2.
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Storage Instruction: Store at-20°C. Avoid freeze/thaw cycles.
Isotype: IgG
Dilution Range: WB: 1:500-1:2000
Gene ID: 6423
Gene Symbol: SFRP2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 141-295 of human SFRP2 (NP_003004.1).
Background This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer.
Tissue Specificity Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
Database Links Reactome: R-HSA-201681
Cellular Localisation Secreted
Protein Name Secreted Frizzled-Related Protein 2
Secreted Apoptosis-Related Protein 1
Alternative Names Anti-Secreted Frizzled-Related Protein 2 antibody
Anti-Frp-2 antibody
Anti-Sfrp-2 antibody
Anti-Secreted Apoptosis-Related Protein 1 antibody
Anti-Sarp-1 antibody
Anti-SFRP2 antibody
Anti-FRP2 antibody
Anti-SARP1 antibody
Anti-FKSG12 antibody
Anti-UNQ361 antibody
Anti-PRO697 antibody

Information sourced from uniprot.org

6 months standard