| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RAB26 (1-60) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
RAB26 |
| Gene ID: |
25837 |
| Uniprot ID: |
RAB26_HUMAN |
| Immunogen Region: |
1-60 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-60 of human RAB26 (NP_055168.2). |
| Immunogen Sequence: |
MSRKKTPKSKGASTPAASTL PTANGARPARSGTALSGPDA PPNGPLQPGRPSLGGGVDFY |
| Tissue Specificity | Predominantly expressed in brain. |
| Function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland. |
| Protein Name | Ras-Related Protein Rab-26 |
| Database Links | Reactome: R-HSA-8873719 |
| Cellular Localisation | Golgi Apparatus MembraneLipid-AnchorCytoplasmic SideCytoplasmic VesicleSecretory Vesicle MembraneNot Localized At The Plasma MembraneInhibition Of S-Geranylgeranyl Cysteine Formation Abolishes Membrane Location |
| Alternative Antibody Names | Anti-Ras-Related Protein Rab-26 antibodyAnti-RAB26 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
