• Immunofluorescence analysis of COS7 cells, using PLCG1 Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-PLC Gamma antibody (STJ95156)


Current Stock:
Host: Rabbit
Applications: WB, IF, ELISA
Reactivity: Human, Mouse, Rat
Short Description: Rabbit polyclonal anti-PLC Gamma antibody is suitable for use in Western Blot, Immunofluorescence and ELISA.
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Concentration: 1 mg/ml
Isotype: IgG
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:5000
Specificity: PLC gamma 1 polyclonal antibody detects endogenous levels of PLC gamma 1 protein.
Gene ID: 5335
Gene Symbol: PLCG1
Immunogen: Synthesized peptide derived from human PLC gamma1 around the non-phosphorylation site of Y1253.
Immunogen Region: 1190-1270 aa
Function Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.
Protein Name 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Gamma-1
Phosphoinositide Phospholipase C-Gamma-1
Phospholipase C-Ii
Phospholipase C-Gamma-1
Database Links Reactome: R-HSA-1169408
Reactome: R-HSA-1236382
Reactome: R-HSA-1251932
Reactome: R-HSA-1489509
Reactome: R-HSA-167021
Reactome: R-HSA-1855204
Reactome: R-HSA-186763
Reactome: R-HSA-202433
Reactome: R-HSA-2029485
Reactome: R-HSA-210990
Reactome: R-HSA-212718
Reactome: R-HSA-2424491
Reactome: R-HSA-2871796
Reactome: R-HSA-2871809
Reactome: R-HSA-418890
Reactome: R-HSA-5218921
Reactome: R-HSA-5637810
Reactome: R-HSA-5654219
Reactome: R-HSA-5654221
Reactome: R-HSA-5654227
Reactome: R-HSA-5654228
Reactome: R-HSA-5655253
Reactome: R-HSA-5655291
Reactome: R-HSA-5655302
Reactome: R-HSA-8853338
Reactome: R-HSA-8853659
Reactome: R-HSA-9026527
Reactome: R-HSA-9027277
Reactome: R-HSA-9034793
Reactome: R-HSA-9664323
Reactome: R-HSA-9664565
Reactome: R-HSA-9665348
Reactome: R-HSA-9665686
Cellular Localisation Cell Projection
Rapidly Redistributed To Ruffles And Lamellipodia Structures In Response To Epidermal Growth Factor (Egf) Treatment
Alternative Antibody Names Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Gamma-1 antibody
Anti-Plc-148 antibody
Anti-Phosphoinositide Phospholipase C-Gamma-1 antibody
Anti-Phospholipase C-Ii antibody
Anti-Plc-Ii antibody
Anti-Phospholipase C-Gamma-1 antibody
Anti-Plc-Gamma-1 antibody
Anti-PLCG1 antibody
Anti-PLC1 antibody

Information sourced from Uniprot.org

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