• STJ73669 Negative Control showing staining of paraffin embedded Human Placenta, with no primary antibody.
  • STJ73669 Negative Control showing staining of paraffin embedded Human Prostate, with no primary antibody.
  • STJ73669 (8µg/ml) staining of paraffin embedded Human Placenta. Heat induced antigen retrieval with citrate buffer Ph 6, HRP-staining.
  • STJ73669 (8µg/ml) staining of paraffin embedded Human Prostate. Heat induced antigen retrieval with citrate buffer pH 6, HRP-staining.

Anti-Plasminogen Activator/PLAU antibody (STJ73669)

SKU:
STJ73669

Current Stock:
Host: Goat
Applications: Pep-ELISA, IHC
Reactivity: Human
Short Description: Goat polyclonal anti-Plasminogen Activator/PLAU antibody is suitable for use in ELISA and Immunohistochemistry.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at-20°C. Minimize freezing and thawing.
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5mg/mL
Isotype: IgG
Dilution Range: ELISA: antibody detection limit dilution 1:16000
IHC-Paraffin embedded Human Prostate and Placenta. 8µg/ml.
Uniprot ID: UROK_HUMAN
Gene ID: 5328
Gene Symbol: PLAU
Immunogen Region: C Terminus
Immunogen Sequence: C-HFLPWIRSHTKEEN
Accession Number: NP_002649.1; NP_001138503.1
Post Translational Modifications Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding. Produced as an inactive single-chain protein (pro-uPA or sc-uPA), is processed into the active disulfide-linked two-chain form of PLAU/uPA by a proteolytic event mediated, at least, by TMPRSS4.
Function Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.
Protein Name Urokinase-Type Plasminogen Activator
U-Plasminogen Activator
Upa Cleaved Into - Urokinase-Type Plasminogen Activator Long Chain A - Urokinase-Type Plasminogen Activator Short Chain A - Urokinase-Type Plasminogen Activator Chain B
Database Links Reactome: R-HSA-6798695
Reactome: R-HSA-75205
Cellular Localisation Secreted
Alternative Antibody Names Anti-Urokinase-Type Plasminogen Activator antibody
Anti-U-Plasminogen Activator antibody
Anti-Upa Cleaved Into - Urokinase-Type Plasminogen Activator Long Chain A - Urokinase-Type Plasminogen Activator Short Chain A - Urokinase-Type Plasminogen Activator Chain B antibody
Anti-PLAU antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance