| Host: | Mouse |
| Applications: | ELISA, WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Note: | FOR RESEARCH USE ONLY (RUO). |
| Short Description: | Mouse polyclonal antibody anti-Phospho-CREB1 is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Formulation: | Lyophilized from sterile filtered PBS solution at a concentration of 1mg/ml. Upon receipt A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers |
| Purification: | Serum IgG fraction was purified by Protein G affinity chromatography. |
| Dilution Range: | ELISA: Use at a concentration range of 1-2ug/ml. Western blot:A suitable range of concentrations of this antibody for WB detection is 2-10 µg/ml. WB analysis mouse hippocampal tissue lysate expressing phospho CREB1. Used as primary antibody. IHC:A su |
| Storage Instruction: | The lyophilized antibody is stable for at least 1 year from date of receipt at-20°C. Upon reconstitution, this antibody can be stored in working aliquots at 2°C-8°C for one month, or at-20°C for six months without detectable loss of activity. Avoid r |
| Gene Symbol: | CREB1 |
| Gene ID: | 1385 |
| Uniprot ID: | CREB1_HUMAN |
| Function | Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. |
| Protein Name | Cyclic Amp-Responsive Element-Binding Protein 1Creb-1Camp-Responsive Element-Binding Protein 1 |
| Database Links | Reactome: R-HSA-111931Reactome: R-HSA-111932Reactome: R-HSA-198693Reactome: R-HSA-199920Reactome: R-HSA-2151201Reactome: R-HSA-2197563Reactome: R-HSA-375165Reactome: R-HSA-400253Reactome: R-HSA-442720Reactome: R-HSA-442729Reactome: R-HSA-442742Reactome: R-HSA-5674400Reactome: R-HSA-881907Reactome: R-HSA-9022692Reactome: R-HSA-9022699Reactome: R-HSA-9022702Reactome: R-HSA-9022707Reactome: R-HSA-9031628Reactome: R-HSA-9609690Reactome: R-HSA-9616222Reactome: R-HSA-9634638Reactome: R-HSA-9660821Reactome: R-HSA-9664323Reactome: R-HSA-9707616 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cyclic Amp-Responsive Element-Binding Protein 1 antibodyAnti-Creb-1 antibodyAnti-Camp-Responsive Element-Binding Protein 1 antibodyAnti-CREB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
