| Host: | Rabbit |
| Applications: | WB, IF |
| Reactivity: | Human, Mouse |
| Short Description: | Rabbit polyclonal primary antibody against P2RX4. |
| Note: | FOR RESEARCH USE ONLY (RUO). |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Formulation: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification: | Affinity purification |
| Storage Instruction: | Store at-20°C. Avoid freeze/thaw cycles. |
| Isotype: | IgG |
| Dilution Range: | WB: 1:500-1:2000IF: 1:10-1:100 |
| Uniprot ID: | P2RX4_HUMAN |
| Gene ID: | 5025 |
| Gene Symbol: | P2RX4 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 55-338 of human P2RX4 (NP_002551.2). |
| Background | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. |
| Function | Receptor for ATP that acts as a ligand-gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin. |
| Database Links | Reactome: R-HSA-139853 |
| Cellular Localisation | MembraneMulti-Pass Membrane Protein |
| Protein Name | P2x Purinoceptor 4P2x4Atp ReceptorPurinergic Receptor |
| Alternative Names | Anti-P2x Purinoceptor 4 antibodyAnti-P2x4 antibodyAnti-Atp Receptor antibodyAnti-Purinergic Receptor antibodyAnti-P2RX4 antibody |
6 months standard
