Anti-NUCKS1 antibody (100-200) (STJ11104177)

Name: Anti-NUCKS1 antibody (100-200) (STJ11104177)
SKU: STJ11104177
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ11104177

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Rabbit polyclonal Nuclear Ubiquitous Casein And Cyclin-Dependent Kinase Substrate 1 (100-200) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	NUCKS1
Gene ID	64710
Uniprot ID	NUCKS_HUMAN
Immunogen Region	100-200
Immunogen Sequence	ASKQREMLMEDVGSEEEQEE EDEAPFQEKDSGSDEDFLME DDDDSDYGSSKKKNKKMVKK SKPERKEKKMPKPRLKATVT PSPVKGKGKVGRPTASKASK E
Specificity	A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NUCKS1 (NP_073568.2).

Tissue Specificity	Widely expressed, with highest levels in thyroid gland, prostate and uterus and in fetal liver, thymus and lung.
Post Translational Modifications	Phosphorylated in an ATM-dependent manner in response to DNA damage. Phosphorylated by CDK1 and casein kinase.
Function	Chromatin-associated protein involved in DNA repair by promoting homologous recombination (HR). Binds double-stranded DNA (dsDNA) and secondary DNA structures, such as D-loop structures, but with less affinity than RAD51AP1.
Protein Name	Nuclear Ubiquitous Casein And Cyclin-Dependent Kinase Substrate 1 P1
Database Links
Cellular Localisation	Nucleus Chromosome
Alternative Antibody Names	Anti-Nuclear Ubiquitous Casein And Cyclin-Dependent Kinase Substrate 1 antibody Anti-P1 antibody Anti-NUCKS1 antibody Anti-NUCKS antibody Anti-JC7 antibody

Information sourced from Uniprot.org