Anti-MYRIP/SLAC2C antibody (C-Term) (STJ70393)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-MYRIP/SLAC2C (C-Term) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 90kDa band observed in Human Brain (Amygdala) lysates (calculated MW of 95.7kDa according to NP_056275.2). Recommended concentration: 0.3-1µg/ml.IHC: Paraffin embedded Huma |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | MYRIP |
| Gene ID | 25924 |
| Uniprot ID | MYRIP_HUMAN |
| Accession Number | NP_056275.2 |
| Immunogen Region | C-Term |
| Immunogen Sequence | KDLMEPALESAVMY |
Additional Info
| Function | Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release. |
| Protein Name | Rab Effector MyripExophilin-8Myosin-Viia- And Rab-Interacting ProteinSynaptotagmin-Like Protein Lacking C2 Domains CSlac2-CSlp Homolog Lacking C2 Domains C |
| Database Links | Reactome: R-HSA-264876Reactome: R-HSA-9824585 |
| Cellular Localisation | CytoplasmPerinuclear RegionCytoplasmic VesicleSecretory VesicleIn Presynaptic And Postsynaptic Areas In Photoreceptor Cells And In The Basal Microvilli Of Retinal Pigment Epithelium CellsAssociated With MelanosomesColocalizes With Actin Filaments |
| Alternative Antibody Names | Anti-Rab Effector Myrip antibodyAnti-Exophilin-8 antibodyAnti-Myosin-Viia- And Rab-Interacting Protein antibodyAnti-Synaptotagmin-Like Protein Lacking C2 Domains C antibodyAnti-Slac2-C antibodyAnti-Slp Homolog Lacking C2 Domains C antibodyAnti-MYRIP antibodyAnti-SLAC2C antibody |
Information sourced from Uniprot.org