| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-MINPP1 (298-487) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
MINPP1 |
| Gene ID: |
9562 |
| Uniprot ID: |
MINP1_HUMAN |
| Immunogen Region: |
298-487 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 298-487 of human MINPP1 (NP_004888.2). |
| Immunogen Sequence: |
KSPWCDVFDIDDAKVLEYLN DLKQYWKRGYGYTINSRSSC TLFQDIFQHLDKAVEQKQRS QPISSPVILQFGHAETLLPL LSLMGYFKDKEPLTAYNYKK QMHRKFRSGLIVPYASNLIF VLYHCENAKTPKEQFRVQML LNEKVLPLAYSQETVSFYED LKNHYKDILQSCQTSEECEL ARANSTSDEL |
| Tissue Specificity | Widely expressed with highest levels in kidney, liver, cerebellum and placenta. |
| Function | Acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). Also acts as a 2,3-bisphosphoglycerate 3-phosphatase, by mediating the dephosphorylation of 2,3-bisphosphoglycerate (2,3-BPG) to produce phospho-D-glycerate without formation of 3-phosphoglycerate. May play a role in bone development (endochondral ossification). May play a role in the transition of chondrocytes from proliferation to hypertrophy. Through the regulation of intracellular inositol polyphosphates, may control intracellular cation homeostasis, including that of calcium and iron, hence affecting free cation availability required for neural cell signaling. |
| Protein Name | Multiple Inositol Polyphosphate Phosphatase 12 -3-Bisphosphoglycerate 3-Phosphatase2 -3-Bpg PhosphataseInositol1 -3 -4 -5-Tetrakisphosphate 3-PhosphataseIns(1 -3 -4 -5p(4 3-Phosphatase |
| Database Links | Reactome: R-HSA-1855231 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Multiple Inositol Polyphosphate Phosphatase 1 antibodyAnti-2 -3-Bisphosphoglycerate 3-Phosphatase antibodyAnti-2 -3-Bpg Phosphatase antibodyAnti-Inositol antibodyAnti-1 -3 -4 -5-Tetrakisphosphate 3-Phosphatase antibodyAnti-Ins(1 -3 -4 -5p(4 3-Phosphatase antibodyAnti-MINPP1 antibodyAnti-MIPP antibodyAnti-UNQ900 antibodyAnti-PRO1917 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and MST1/STK4 knockout (KO) HeLa cells, using [KO Validated] MST1/STK4 Rabbit polyclonal antibody (STJ11100073) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/89143/357593/STJ11100073_1__61039.1713121731.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and MST1/STK4 knockout (KO) HeLa cells, using [KO Validated] MST1/STK4 Rabbit polyclonal antibody (STJ11100073) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")