||Human, Mouse, Rat
||Goat polyclonal anti-Microtubule Associated Protein 2 (MAP2) antibody is suitable for use in Western Blot and Immunofluorescence.
||FOR RESEARCH USE ONLY (RUO).
||100 ul in PBS + 50% glycerol and 5 mm NaN3
||This antibody was protein g purified from serum.
||Store at-20°C, and avoid repeated freeze-thaw cycles.
||WB 1:1, 000IF 1:500
||recombinant human MAP2 protein expressed in and purified from E. Coli
| Post Translational Modifications || Phosphorylated at serine residues in K-X-G-S motifs by MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), causing detachment from microtubules, and their disassembly. Isoform 2 is probably phosphorylated by PKA at Ser-323, Ser-354 and Ser-386 and by FYN at Tyr-67. The interaction with KNDC1 enhances MAP2 threonine phosphorylation. |
| Function || The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. |
| Protein Name || Microtubule-Associated Protein 2Map-2 |
| Cellular Localisation || CytoplasmCytoskeletonCell ProjectionDendrite |
| Alternative Antibody Names || Anti-Microtubule-Associated Protein 2 antibodyAnti-Map-2 antibodyAnti-MAP2 antibody |
Information sourced from Uniprot.org
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