Anti-Kappa antibody [IHC610] (STJA0042014)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2a
ImmunogenHuman Kappa protein.
General Information
| Short Description | Mouse monoclonal anti-Kappa for use in IHC-p in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-p |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | IHC610 |
| Isotype | IgG2a |
| Conjugation | Unconjugated |
| Dilution Range | 1:100-1:200 |
| Formulation | Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide |
| Storage Instruction | Store at 2-8°C for up to 1 year. Do not freeze. |
Target Information
| Immunogen | Human Kappa protein. |
| Specificity | Tested and validated on tonsil tissue. |
Additional Info
| Background | Anti-Kappa recognizes surface immunoglobulin on normal and neoplastic B-cells, and has been indicated as a potential aid in the identification on leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas, where the expression on a single light chain class is restricted. The determination on light chain ratio is critical in evaluating B-cell neoplasms, as the majority on B-cell lymphomas express either kappa or lambda light chains, while a mixture on kappa and lambda is characteristic on reactive proliferations. In paraffin-embedded tissue, Anti-Kappa displays strong staining on kappa-positive plasma cells, as well as cells that have absorbed exogenous immunoglobulins. |
Information sourced from Uniprot.org