• Western blot analysis of extracts of HepG2 cells, using TGF beta Receptor II antibody (STJ11101605) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 10s.

Anti-Integrin alpha 2 antibody [ARC0457] (STJ11101605)

SKU:
STJ11101605

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Host: Rabbit
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Short Description: Rabbit monoclonal anti-Integrin alpha 2 antibody is suitable for use in Western Blot and Immunohistochemistry.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Monoclonal
Clone ID: ARC0457
Conjugation: Unconjugated
Formulation: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Purification: Affinity purification
Storage Instruction: Store at-20°C. Avoid freeze/thaw cycles.
Isotype: IgG
Dilution Range: WB: 1:500-1:2000
IHC: 1:50-1:200
Uniprot ID: ITA2_HUMAN
Gene ID: 3673
Gene Symbol: ITGA2
Immunogen: A synthesized peptide derived from human Integrin alpha 2
Function Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human rotavirus A. (Microbial infection) Integrin ITGA2:ITGB1 acts as a receptor for Human echoviruses 1 and 8.
Protein Name Integrin Alpha-2
Cd49 Antigen-Like Family Member B
Collagen Receptor
Platelet Membrane Glycoprotein Ia
Gpia
Vla-2 Subunit Alpha
Cd Antigen Cd49b
Database Links Reactome: R-HSA-216083
Reactome: R-HSA-3000157
Reactome: R-HSA-3000170
Reactome: R-HSA-3000178
Reactome: R-HSA-447041
Reactome: R-HSA-75892
Reactome: R-HSA-8874081
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Integrin Alpha-2 antibody
Anti-Cd49 Antigen-Like Family Member B antibody
Anti-Collagen Receptor antibody
Anti-Platelet Membrane Glycoprotein Ia antibody
Anti-Gpia antibody
Anti-Vla-2 Subunit Alpha antibody
Anti-Cd Antigen Cd49b antibody
Anti-ITGA2 antibody
Anti-CD49B antibody

Information sourced from Uniprot.org

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