• Western blot analysis of extracts of mouse small intestine, using GUCA2B antibody (STJ110688) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
  • Western blot analysis of extracts of mouse small intestine, using GUCA2B antibody (STJ110688) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-GUCA2B antibody (1-100) (STJ110688)

SKU:
STJ110688

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-GUCA2B (1-100) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: GUCA2B
Gene ID: 2981
Uniprot ID: GUC2B_HUMAN
Immunogen Region: 1-100
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GUCA2B (NP_009033.1).
Immunogen Sequence: MGCRAASGLLPGVAVVLLLL LQSTQSVYIQYQGFRVQLES MKKLSDLEAQWAPSPRLQAQ SLLPAVCHHPALPQDLQPVC ASQEASSIFKTLRTIANDDC
Tissue Specificity Stomach and intestine.
Function Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.
Protein Name Guanylate Cyclase Activator 2b Cleaved Into - Guanylate Cyclase C-Activating Peptide 2
Guanylate Cyclase C-Activating Peptide Ii
Gcap-Ii - Uroguanylin
Ugn
Database Links Reactome: R-HSA-8935690
Cellular Localisation Secreted
Alternative Antibody Names Anti-Guanylate Cyclase Activator 2b Cleaved Into - Guanylate Cyclase C-Activating Peptide 2 antibody
Anti-Guanylate Cyclase C-Activating Peptide Ii antibody
Anti-Gcap-Ii - Uroguanylin antibody
Anti-Ugn antibody
Anti-GUCA2B antibody

Information sourced from Uniprot.org

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