• Western blot analysis of GSDMC Antibody. The lane on the right is blocked with the GSDMC peptide.
  • Western blot analysis of the lysates from HepG2 cells using GSDMC antibody.
  • Western blot analysis of various cells using Gasdermin C Polyclonal Antibody diluted at 1:500

Anti-Gasdermin C antibody (STJ93220)

SKU:
STJ93220
Current Stock:
Host: Rabbit
Applications: WB, ELISA
Reactivity: Human
Short Description: Rabbit polyclonal primary antibody against Gasdermin C.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Concentration: 1 mg/ml
Isotype: IgG
Dilution Range: WB 1:500-1:2000
ELISA 1:10000
Specificity: Gasdermin C polyclonal antibody detects endogenous levels of Gasdermin C protein.
Uniprot ID: GSDMC_HUMAN
Gene ID: 56169
Gene Symbol: GSDMC
Immunogen: Synthesized peptide derived from human Gasdermin C
Immunogen Region: 80-160 aa, Internal
Tissue Specificity Expressed mainly in trachea and spleen. In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium.
Function The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown (Probable).
Cellular Localisation Cytoplasm
Cytosol
Cell Membrane
Protein Name Gasdermin-C
Melanoma-Derived Leucine Zipper-Containing Extranuclear Factor
Alternative Names Anti-Gasdermin-C antibody
Anti-Melanoma-Derived Leucine Zipper-Containing Extranuclear Factor antibody
Anti-GSDMC antibody
Anti-MLZE antibody
6 months standard