| Host: | Rabbit |
| Applications: | WB, ELISA |
| Reactivity: | Human |
| Short Description: | Rabbit polyclonal primary antibody against Gasdermin C. |
| Note: | FOR RESEARCH USE ONLY (RUO). |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen. |
| Storage Instruction: | Store at-20°C, and avoid repeat freeze-thaw cycles. |
| Concentration: | 1 mg/ml |
| Isotype: | IgG |
| Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
| Specificity: | Gasdermin C polyclonal antibody detects endogenous levels of Gasdermin C protein. |
| Uniprot ID: | GSDMC_HUMAN |
| Gene ID: | 56169 |
| Gene Symbol: | GSDMC |
| Immunogen: | Synthesized peptide derived from human Gasdermin C |
| Immunogen Region: | 80-160 aa, Internal |
| Tissue Specificity | Expressed mainly in trachea and spleen. In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium. |
| Function | The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown (Probable). |
| Cellular Localisation | CytoplasmCytosolCell Membrane |
| Protein Name | Gasdermin-CMelanoma-Derived Leucine Zipper-Containing Extranuclear Factor |
| Alternative Names | Anti-Gasdermin-C antibodyAnti-Melanoma-Derived Leucine Zipper-Containing Extranuclear Factor antibodyAnti-GSDMC antibodyAnti-MLZE antibody |
Information sourced from Uniprot.org
6 months standard
