Host: | Rabbit |
Applications: | WB, ELISA |
Reactivity: | Human |
Short Description: | Rabbit polyclonal primary antibody against Gasdermin C. |
Note: | FOR RESEARCH USE ONLY (RUO). |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Formulation: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen. |
Storage Instruction: | Store at-20°C, and avoid repeat freeze-thaw cycles. |
Concentration: | 1 mg/ml |
Isotype: | IgG |
Dilution Range: | WB 1:500-1:2000ELISA 1:10000 |
Specificity: | Gasdermin C polyclonal antibody detects endogenous levels of Gasdermin C protein. |
Uniprot ID: | GSDMC_HUMAN |
Gene ID: | 56169 |
Gene Symbol: | GSDMC |
Immunogen: | Synthesized peptide derived from human Gasdermin C |
Immunogen Region: | 80-160 aa, Internal |
Tissue Specificity | Expressed mainly in trachea and spleen. In the esophagus, expressed in differentiating cells and probably in differentiated cells. Also detected in gastric epithelium. |
Function | The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores. The physiological relevance of this observation is unknown (Probable). |
Cellular Localisation | CytoplasmCytosolCell Membrane |
Protein Name | Gasdermin-CMelanoma-Derived Leucine Zipper-Containing Extranuclear Factor |
Alternative Names | Anti-Gasdermin-C antibodyAnti-Melanoma-Derived Leucine Zipper-Containing Extranuclear Factor antibodyAnti-GSDMC antibodyAnti-MLZE antibody |
Information sourced from Uniprot.org
6 months standard