Anti-GALNT3 antibody (43-633) (STJ115920)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal GALNT3 (43-633) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GALNT3 |
| Gene ID | 2591 |
| Uniprot ID | GALT3_HUMAN |
| Immunogen Region | 43-633 |
| Immunogen Sequence | VQYSKEESRMERNMKNKNKM LDLMLEAVNNIKDAMPKMQI GAPVRQNIDAGERPCLQGYY TAAELKPVLDRPPQDSNAPG ASGKAFKTTNLSVEEQKEKE RGEAKHCFNAFASDRISL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 43-160 of human GALNT3 (NP_004473.2). |
Additional Info
| Tissue Specificity | Expressed in organs that contain secretory epithelial glands. Highly expressed in pancreas, skin, kidney and testis. Weakly expressed in prostate, ovary, intestine and colon. Also expressed in placenta and lung and fetal lung and fetal kidney. |
| Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, MUC2, MUC1A and MUC5AC. Probably glycosylates fibronectin in vivo. Glycosylates FGF23. |
| Protein Name | Polypeptide N-Acetylgalactosaminyltransferase 3Polypeptide Galnac Transferase 3Galnac-T3Pp-Gantase 3Protein-Udp Acetylgalactosaminyltransferase 3Udp-Galnac -Polypeptide N-Acetylgalactosaminyltransferase 3 |
| Database Links | Reactome: R-HSA-190372Reactome: R-HSA-5083625Reactome: R-HSA-913709 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinResides Preferentially In The Trans And Medial Parts Of The Golgi Stack |
| Alternative Antibody Names | Anti-Polypeptide N-Acetylgalactosaminyltransferase 3 antibodyAnti-Polypeptide Galnac Transferase 3 antibodyAnti-Galnac-T3 antibodyAnti-Pp-Gantase 3 antibodyAnti-Protein-Udp Acetylgalactosaminyltransferase 3 antibodyAnti-Udp-Galnac -Polypeptide N-Acetylgalactosaminyltransferase 3 antibodyAnti-GALNT3 antibody |
Information sourced from Uniprot.org