| Host: |
Rabbit |
| Applications: |
WB, IF, ELISA |
| Reactivity: |
Human, Rat, Mouse |
| Note: |
FOR RESEARCH USE ONLY (RUO). |
| Short Description: |
Rabbit polyclonal antibody anti-Follicle-Stimulating Hormone Receptor (250-330 Internal) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IF 1:100-300ELISA 1:5000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FSHR |
| Gene ID: |
2492 |
| Uniprot ID: |
FSHR_HUMAN |
| Immunogen Region: |
250-330 Internal |
| Specificity: |
FSHR polyclonal antibody (Follicle-Stimulating Hormone Receptor) binds to endogenous Follicle-Stimulating Hormone Receptor at the amino acid region 250-330 Internal. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human FSHR at amino acid range 278-327 |
| Post Translational Modifications | Sulfated. N-glycosylated.indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone. |
| Function | G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. |
| Protein Name | Follicle-Stimulating Hormone ReceptorFsh-RFollitropin Receptor |
| Database Links | Reactome: R-HSA-375281Reactome: R-HSA-418555Reactome: R-HSA-9660821 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Follicle-Stimulating Hormone Receptor antibodyAnti-Fsh-R antibodyAnti-Follitropin Receptor antibodyAnti-FSHR antibodyAnti-LGR1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
