• Western blot analysis of the lysates from HeLa cells using FZD9 antibody.
  • Western blot analysis of FZD9 Antibody. The lane on the right is blocked with the FZD9 peptide.

Anti-Frizzled-9 antibody (STJ93153)

SKU:
STJ93153
Current Stock:
Host: Rabbit
Applications: WB, ELISA
Reactivity: Human,Mouse,Rat
Short Description: Rabbit polyclonal primary antibody against Frizzled-9.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Concentration: 1 mg/ml
Isotype: IgG
Dilution Range: WB 1:500-1:2000
ELISA 1:5000
Specificity: Frizzled-9 polyclonal antibody detects endogenous levels of Frizzled-9 protein.
Uniprot ID: FZD9_HUMAN
Gene ID: 8326
Gene Symbol: FZD9
Immunogen: Synthesized peptide derived from human Frizzled-9
Immunogen Region: 10-90 aa, N-terminal
Tissue Specificity Expressed predominantly in adult and fetal brain, testis, eye, skeletal muscle and kidney. Moderately expressed in pancreas, thyroid, adrenal cortex, small intestine and stomach. Detected in fetal liver and kidney. Expressed in neural progenitor cells.
Post Translational Modifications Ubiquitinated by ZNRF3, leading to its degradation by the proteasome.
Function Receptor for WNT2 that is coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. Plays a role in neuromuscular junction (NMJ) assembly by negatively regulating the clustering of acetylcholine receptors (AChR) through the beta-catenin canonical signaling pathway. May play a role in neural progenitor cells (NPCs) viability through the beta-catenin canonical signaling pathway by negatively regulating cell cycle arrest leading to inhibition of neuron apoptotic process. During hippocampal development, regulates neuroblast proliferation and apoptotic cell death. Controls bone formation through non canonical Wnt signaling mediated via ISG15. Positively regulates bone regeneration through non canonical Wnt signaling.
Database Links Reactome: R-HSA-373080
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Relocalizes Dvl1 To The Cell Membrane Leading To Phosphorylation Of Dvl1 And Axin1 Relocalization To The Cell Membrane
Protein Name Frizzled-9
Fz-9
Hfz9
Fze6
Cd Antigen Cd349
Alternative Names Anti-Frizzled-9 antibody
Anti-Fz-9 antibody
Anti-Hfz9 antibody
Anti-Fze6 antibody
Anti-Cd Antigen Cd349 antibody
Anti-FZD9 antibody
Anti-FZD3 antibody
6 months standard