| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CXCR5 (193-372) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CXCR5 |
| Gene ID: |
643 |
| Uniprot ID: |
CXCR5_HUMAN |
| Immunogen Region: |
193-372 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 193-372 of human CXCR5 (NP_001707.1). |
| Immunogen Sequence: |
GHHNNSLPRCTFSQENQAET HAWFTSRFLYHVAGFLLPML VMGWCYVGVVHRLRQAQRRP QRQKAVRVAILVTSIFFLCW SPYHIVIFLDTLARLKAVDN TCKLNGSLPVAITMCEFLGL AHCCLNPMLYTFAGVKFRSD LSRLLTKLGCTGPASLCQLF PSWRRSSLSESENATSLTTF |
| Tissue Specificity | Expression in mature B-cells and Burkitt lymphoma cells. |
| Function | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. |
| Protein Name | C-X-C Chemokine Receptor Type 5Cxc-R5Cxcr-5Burkitt Lymphoma Receptor 1Monocyte-Derived Receptor 15Mdr-15Cd Antigen Cd185 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-C-X-C Chemokine Receptor Type 5 antibodyAnti-Cxc-R5 antibodyAnti-Cxcr-5 antibodyAnti-Burkitt Lymphoma Receptor 1 antibodyAnti-Monocyte-Derived Receptor 15 antibodyAnti-Mdr-15 antibodyAnti-Cd Antigen Cd185 antibodyAnti-CXCR5 antibodyAnti-BLR1 antibodyAnti-MDR15 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
