| Short Description : | Rabbit monoclonal CRP (125-224) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S1MR |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:1000-1:2000IHC-P:1:200-1:800ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CRP |
| Gene ID: | 1401 |
| Uniprot ID: | CRP_HUMAN |
| Immunogen Region: | 125-224 |
| Immunogen Sequence: | VEFWVDGKPRVRKSLKKGYT VGAEASIILGQEQDSFGGNF EGSQSLVGDIGNVNMWDFVL SPDEINTIYLGGPFSPNVLN WRALKYEVQGEVFTKPQLWP |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 125-224 of human C-Reactive Protein (CRP) (P02741). |
| Tissue Specificity | Found in plasma. |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Protein Name | C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 |
| Database Links | Reactome: R-HSA-173623 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 antibodyAnti-CRP antibodyAnti-PTX1 antibody |
Information sourced from Uniprot.org
