• Western blot analysis of lysates from 293 and A549 cells, treated with etoposide 25uM 1h, using C1R (light chain, Cleaved-Ile464) Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using Cleaved-C1r LC (I464) Polyclonal Antibody

Anti-Cleaved-C1R-I464 antibody (445-494 aa) (STJ90018)

SKU:
STJ90018

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cleaved-Complement C1r subcomponent-I464 (445-494 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: C1R
Gene ID: 715
Uniprot ID: C1R_HUMAN
Immunogen Region: 445-494 aa
Specificity: Cleaved-C1r LC (I464) Polyclonal Antibody detects endogenous levels of fragment of activated C1r LC protein resulting from cleavage adjacent to I464.
Immunogen: The antiserum was produced against synthesized peptide derived from the human C1R at the amino acid range 445-494
Function C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Protein Name Complement C1r Subcomponent
Complement Component 1 Subcomponent R Cleaved Into - Complement C1r Subcomponent Heavy Chain - Complement C1r Subcomponent Light Chain
Database Links Reactome: R-HSA-166663
Reactome: R-HSA-173623
Reactome: R-HSA-977606
Cellular Localisation Secreted
Alternative Antibody Names Anti-Complement C1r Subcomponent antibody
Anti-Complement Component 1 Subcomponent R Cleaved Into - Complement C1r Subcomponent Heavy Chain - Complement C1r Subcomponent Light Chain antibody
Anti-C1R antibody

Information sourced from Uniprot.org

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