• Western blot analysis of lysates from MCF-7 cells, using CLCN4 Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of RAT-MUSLE cells using CLC-4 Polyclonal Antibody diluted at 1:500
  • Immunofluorescence analysis of HUVEC cells, using CLCN4 Antibody. The picture on the right is blocked with the synthesized peptide.
  • Western blot analysis of various cells using CLC-4 Polyclonal Antibody diluted at 1:500

Anti-CLCN4 antibody (221-270 aa) (STJ92324)

SKU:
STJ92324

Current Stock:
Host: Rabbit
Applications: WB/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-H+/Cl-exchange transporter 4 (221-270 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:40000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CLCN4
Gene ID: 1183
Uniprot ID: CLCN4_HUMAN
Immunogen Region: 221-270 aa
Specificity: CLC-4 Polyclonal Antibody detects endogenous levels of CLC-4 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the human CLCN4 at the amino acid range 221-270
Function Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons. The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons. The presence of conserved gating glutamate residues is typical for family members that function as antiporters.
Protein Name H(+/Cl(- Exchange Transporter 4
Chloride Channel Protein 4
Clc-4
Chloride Transporter Clc-4
Database Links Reactome: R-HSA-2672351
Cellular Localisation Early Endosome Membrane
Multi-Pass Membrane Protein
Late Endosome Membrane
Endoplasmic Reticulum Membrane
Lysosome Membrane
Recycling Endosome Membrane
Localizes To Late Endosome Membrane
Lysosome Membrane And Recycling Endosome Membrane In The Presence Of Clcn3
Alternative Antibody Names Anti-H(+/Cl(- Exchange Transporter 4 antibody
Anti-Chloride Channel Protein 4 antibody
Anti-Clc-4 antibody
Anti-Chloride Transporter Clc-4 antibody
Anti-CLCN4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance