Anti-CERK antibody (STJA0009216)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human CERK
General Information
| Short Description | Rabbit polyclonal anti-Ceramide kinase for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CERK |
| Gene ID | 64781 |
| Uniprot ID | CERK1_HUMAN |
| Immunogen | Synthesized peptide derived from human CERK |
| Specificity | This antibody detects endogenous levels of CERK at Human, Mouse |
Additional Info
| Function | Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Shows a greater preference for D-erythro isomer of ceramides. Binds phosphoinositides. |
| Protein Name | Ceramide KinaseHcerkAcylsphingosine KinaseLipid Kinase 4Lk4 |
| Database Links | Reactome: R-HSA-9840309 |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Ceramide Kinase antibodyAnti-Hcerk antibodyAnti-Acylsphingosine Kinase antibodyAnti-Lipid Kinase 4 antibodyAnti-Lk4 antibodyAnti-CERK antibodyAnti-KIAA1646 antibody |
Information sourced from Uniprot.org