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Polyclonal Antibodies
Anti-CDC16 antibody (181-230 aa) (STJ92152)

Western blot analysis of lysates from NIH/3T3 cells, using APC6 Antibody. The lane on the right is blocked with the synthesized peptide.
Immunohistochemical analysis of paraffin-embedded Human brain. Antibody was diluted at 1:100 (4°C overnight). High-pressure and temperature Tris-EDTA, pH8.0 was used for antigen retrieval. Negetive contrl (right) obtaned from antibody was pre-absorbed by immunogen peptide.

Anti-CDC16 antibody (181-230 aa) (STJ92152)

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STJ92152

£46.00 - £226.00

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General Information
Product Properties
Target Information
Additional Info
Warranty Information

Host:	Rabbit
Applications:	WB/IHC/IF/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Rabbit polyclonal antibody anti-Cell division cycle protein 16 homolog (181-230 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.

Clonality:	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:	1 mg/mL
Dilution Range:	WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CDC16
Gene ID:	8881
Uniprot ID:	CDC16_HUMAN
Immunogen Region:	181-230 aa
Specificity:	Cdc16 Polyclonal Antibody detects endogenous levels of Cdc16 protein.
Immunogen:	The antiserum was produced against synthesized peptide derived from the human APC6 at the amino acid range 181-230

Function	Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Protein Name	Cell Division Cycle Protein 16 Homolog Anaphase-Promoting Complex Subunit 6 Apc6 Cdc16 Homolog Cdc16hs Cyclosome Subunit 6
Database Links	Reactome: R-HSA-141430 Reactome: R-HSA-174048 Reactome: R-HSA-174084 Reactome: R-HSA-174154 Reactome: R-HSA-174178 Reactome: R-HSA-174184 Reactome: R-HSA-176407 Reactome: R-HSA-176408 Reactome: R-HSA-176409 Reactome: R-HSA-176412 Reactome: R-HSA-179409 Reactome: R-HSA-2467813 Reactome: R-HSA-2559582 Reactome: R-HSA-68867 Reactome: R-HSA-69017 Reactome: R-HSA-8853884 Reactome: R-HSA-9687136 Reactome: R-HSA-983168
Cellular Localisation	Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Spindle Colocalizes With Cdc27 To The Centrosome At All Stages Of The Cell Cycle And To The Mitotic Spindle
Alternative Antibody Names	Anti-Cell Division Cycle Protein 16 Homolog antibody Anti-Anaphase-Promoting Complex Subunit 6 antibody Anti-Apc6 antibody Anti-Cdc16 Homolog antibody Anti-Cdc16hs antibody Anti-Cyclosome Subunit 6 antibody Anti-CDC16 antibody Anti-ANAPC6 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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