• Western blot analysis of extracts of mouse lung, using CD226 antibody (STJ112320) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.

Anti-CD226 antibody (19-254) (STJ112320)

SKU:
STJ112320

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CD226 (19-254) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CD226
Gene ID: 10666
Uniprot ID: CD226_HUMAN
Immunogen Region: 19-254
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-254 of human CD226 (NP_006557.2).
Immunogen Sequence: EEVLWHTSVPFAENMSLECV YPSMGILTQVEWFKIGTQQD SIAIFSPTHGMVIRKPYAER VYFLNSTMASNNMTLFFRNA SEDDVGYYSCSLYTYPQGTW QKVIQVVQSDSFEAAVPSNS HIVSEPGKNVTLTCQPQMTW PVQAVRWEKIQPRQIDLLTY CNLVHGRNFTSKFPRQIVSN CSHGRWSVIVIPDVTVSDSG LYRCYLQASAGENETFVMRL TVAEGKTDNQYTLFVA
Tissue Specificity Expressed by peripheral blood T-lymphocytes.
Function Involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T-lymphocyte (CTL) and NK cell. Cell surface receptor for NECTIN2. Upon ligand binding, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Competes with PVRIG for NECTIN2-binding.
Protein Name Cd226 Antigen
Dnax Accessory Molecule 1
Dnam-1
Cd Antigen Cd226
Database Links Reactome: R-HSA-198933
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-Cd226 Antigen antibody
Anti-Dnax Accessory Molecule 1 antibody
Anti-Dnam-1 antibody
Anti-Cd Antigen Cd226 antibody
Anti-CD226 antibody
Anti-DNAM1 antibody

Information sourced from Uniprot.org

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