• Anti-CD10 antibody (STJ16101693)

Anti-CD10 antibody (STJ16101693)

SKU:
STJ16101693

Current Stock:
Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Mouse monoclonal antibody anti-CD10 is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Conjugation: Unconjugated
Isotype: IgG1
Formulation: Tissue culture supernatant with sodium azide
Dilution Range: IHC-P (1:100)
Storage Instruction: Store at 2-8°C upon receipt.
Background CD10 antigen, also called neprilysin, is a 100 kD cell surface metalloendopeptidase which inactivates a variety of biologically active peptides. It was initially identified as the common acute lymphoblastic leukemia antigen (CALLA) and was thought to be tumor-specific. Subsequent studies, however, have shown that CD10 antigen is expressed on the surface of a wide variety of normal and neoplastic cells. In other lymphoid malignancies, CD10 antigen is reported to be expressed on cells of lymphoblastic, Burkitt s and follicular lymphomas. CD10 antigen has been identified on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. It is also expressed in various non-lymphoid cells and tissues, such as breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. (G. McIntosh et al. American Journal of Pathology. 154 (1) : 77-82 (1999) ).

Information sourced from Uniprot.org

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