• Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using CAD Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-CAD antibody (400-480 aa) (STJ91958)

SKU:
STJ91958

Current Stock:
Host: Rabbit
Applications: IHC-P, ELISA
Reactivity: Human, Mouse
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Rabbit polyclonal antibody Anti-CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase (400-480 aa) is suitable for use in Immunohistochemistry and ELISA.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Concentration: 1 mg/ml
Dilution Range: IHC 1:100-1:300
ELISA 1:20000
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Gene Symbol: CAD
Gene ID: 790
Uniprot ID: PYR1_HUMAN
Immunogen Region: 400-480 aa
Specificity: CAD polyclonal antibody detects endogenous levels of CAD protein.
Immunogen: Synthesized peptide derived from human CAD around the non-phosphorylation site of T456.
Function This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase).
Protein Name Cad Protein Includes - Glutamine-Dependent Carbamoyl-Phosphate Synthase - Aspartate Carbamoyltransferase - Dihydroorotase
Database Links Reactome: R-HSA-500753
Cellular Localisation Cytoplasm
Nucleus
Cytosolic And Unphosphorylated In Resting Cells
Translocates To The Nucleus In Response To Egf Stimulation
Nuclear Import Promotes Optimal Cell Growth
Alternative Antibody Names Anti-Cad Protein Includes - Glutamine-Dependent Carbamoyl-Phosphate Synthase - Aspartate Carbamoyltransferase - Dihydroorotase antibody
Anti-CAD antibody

Information sourced from Uniprot.org

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