| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-AP3M1 (219-418) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AP3M1 |
| Gene ID: |
26985 |
| Uniprot ID: |
AP3M1_HUMAN |
| Immunogen Region: |
219-418 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 219-418 of human AP3M1 (NP_036227.1). |
| Immunogen Sequence: |
SLSFMNPRLLDDVSFHPCIR FKRWESERVLSFIPPDGNFR LISYRVSSQNLVAIPVYVKH SISFKENSSCGRFDITIGPK QNMGKTIEGITVTVHMPKVV LNMNLTPTQGSYTFDPVTKV LTWDVGKITPQKLPSLKGLV NLQSGAPKPEENPSLNIQFK IQQLAISGLKVNRLDMYGEK YKPFKGVKYVTKAGKFQVRT |
| Function | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
| Protein Name | Ap-3 Complex Subunit Mu-1Ap-3 Adaptor Complex Mu3a SubunitAdaptor-Related Protein Complex 3 Subunit Mu-1Mu-Adaptin 3aMu3a-Adaptin |
| Database Links | Reactome: R-HSA-390471 |
| Cellular Localisation | Golgi ApparatusCytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Antibody Names | Anti-Ap-3 Complex Subunit Mu-1 antibodyAnti-Ap-3 Adaptor Complex Mu3a Subunit antibodyAnti-Adaptor-Related Protein Complex 3 Subunit Mu-1 antibodyAnti-Mu-Adaptin 3a antibodyAnti-Mu3a-Adaptin antibodyAnti-AP3M1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
