| Host: |
Rabbit |
| Applications: |
WB/IHC/IF/ELISA |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Centrosome-associated protein ALMS1 (1530-1610 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ALMS1 |
| Gene ID: |
7840 |
| Uniprot ID: |
ALMS1_HUMAN |
| Immunogen Region: |
1530-1610 aa |
| Specificity: |
ALMS1 Polyclonal Antibody detects endogenous levels of ALMS1 protein. |
| Immunogen: |
Synthesized peptide derived from ALMS1 at the amino acid range 1530-1610 |
| Function | Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells. |
| Protein Name | Centrosome-Associated Protein Alms1Alstrom Syndrome Protein 1 |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5620912Reactome: R-HSA-8854518 |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCilium Basal BodySpindle PoleAssociated With Centrosomes And Basal Bodies At The Base Of Primary CiliaSpecifically Locates To The Proximal Ends Of Centrioles And Basal BodiesColocalizes Partially With Ncapd2 At These SitesDuring Mitosis Localizes To Both Spindle Poles |
| Alternative Antibody Names | Anti-Centrosome-Associated Protein Alms1 antibodyAnti-Alstrom Syndrome Protein 1 antibodyAnti-ALMS1 antibodyAnti-KIAA0328 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
