| Host: |
Rabbit |
| Applications: |
IHC/IF |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-A-kinase anchor protein 9 (2610-2690 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC-P 1:50-300IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
AKAP9 |
| Gene ID: |
10142 |
| Uniprot ID: |
AKAP9_HUMAN |
| Immunogen Region: |
2610-2690 aa |
| Specificity: |
AKAP9 Polyclonal Antibody detects endogenous levels of protein. |
| Immunogen: |
Synthesized peptide derived from the human protein at the amino acid range 2610-2690 |
| Function | Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Required to maintain the integrity of the Golgi apparatus. Required for microtubule nucleation at the cis-side of the Golgi apparatus. Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. In complex with PDE4DIP isoform 13/MMG8/SMYLE, recruits CAMSAP2 to the Golgi apparatus and tethers non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. In complex with PDE4DIP isoform 13/MMG8/SMYLE, EB1/MAPRE1 and CDK5RAP2, contributes to microtubules nucleation and extension also from the centrosome to the cell periphery. Isoform 4: Associated with the N-methyl-D-aspartate receptor and is specifically found in the neuromuscular junction (NMJ) as well as in neuronal synapses, suggesting a role in the organization of postsynaptic specializations. |
| Protein Name | A-Kinase Anchor Protein 9Akap-9A-Kinase Anchor Protein 350 KdaAkap 350Hgakap 350A-Kinase Anchor Protein 450 KdaAkap 450Akap 120-Like ProteinCentrosome- And Golgi-Localized Pkn-Associated ProteinCg-NapProtein HyperionProtein Kinase A-Anchoring Protein 9Prka9Protein Yotiao |
| Database Links | Reactome: R-HSA-2565942Reactome: R-HSA-380259Reactome: R-HSA-380270Reactome: R-HSA-380284Reactome: R-HSA-380320Reactome: R-HSA-5576890Reactome: R-HSA-5576893Reactome: R-HSA-5620912Reactome: R-HSA-6802952Reactome: R-HSA-8854518 |
| Cellular Localisation | Golgi ApparatusCytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCytoplasmic In Parietal CellsRecruited To The Golgi Apparatus By Gm130/Golga2Localization At The Centrosome Versus Golgi Apparatus May Be Cell Line-DependentIn Skbr3 And Hek293f CellsExclusively Located At The CentrosomeIn HelaMda-Mb231 And Rpe-1 CellsDetected At The Golgi ApparatusIn Sk-Br-3 CellsRecruited To The Centrosome In The Presence Of Cdk5rap2 |
| Alternative Antibody Names | Anti-A-Kinase Anchor Protein 9 antibodyAnti-Akap-9 antibodyAnti-A-Kinase Anchor Protein 350 Kda antibodyAnti-Akap 350 antibodyAnti-Hgakap 350 antibodyAnti-A-Kinase Anchor Protein 450 Kda antibodyAnti-Akap 450 antibodyAnti-Akap 120-Like Protein antibodyAnti-Centrosome- And Golgi-Localized Pkn-Associated Protein antibodyAnti-Cg-Nap antibodyAnti-Protein Hyperion antibodyAnti-Protein Kinase A-Anchoring Protein 9 antibodyAnti-Prka9 antibodyAnti-Protein Yotiao antibodyAnti-AKAP9 antibodyAnti-AKAP350 antibodyAnti-AKAP450 antibodyAnti-KIAA0803 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
