| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-ADCYAP1R1 (25-140) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ADCYAP1R1 |
| Gene ID: |
117 |
| Uniprot ID: |
PACR_HUMAN |
| Immunogen Region: |
25-140 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 25-140 of ADCYAP1R1 (NP_001109.2). |
| Immunogen Sequence: |
CIFKKEQAMCLEKIQRANEL MGFNDSSPGCPGMWDNITCW KPAHVGEMVLVSCPELFRIF NPDQVWETETIGESDFGDSN SLDLSDMGVVSRNCTEDGWS EPFPHYFDACGFDEYE |
| Tissue Specificity | Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta. |
| Function | This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. |
| Protein Name | Pituitary Adenylate Cyclase-Activating Polypeptide Type I ReceptorPacap Type I ReceptorPacap-R-1Pacap-R1 |
| Database Links | Reactome: R-HSA-187024Reactome: R-HSA-418555Reactome: R-HSA-420092 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor antibodyAnti-Pacap Type I Receptor antibodyAnti-Pacap-R-1 antibodyAnti-Pacap-R1 antibodyAnti-ADCYAP1R1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
