| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human, Mouse, Rat |
| Note: |
FOR RESEARCH USE ONLY (RUO). |
| Short Description: |
Rabbit polyclonal antibody anti-Acetyl-Histone H2A type 1 and Histone H2A type 2-A and Histone H2A type 3-Lys9 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS, pH 7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
| Purification: |
The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography. |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
H2AC18.H2AC19H2AW723790/833792815H2A2A_HUMANH2A3_HUMANH2A1_HUMAN |
| Specificity: |
Acetyl-Histone H2A-Lys9 polyclonal antibody (Histone H2A type 1 and Histone H2A type 2-A and Histone H2A type 3) binds to endogenous Histone H2A type 1 and Histone H2A type 2-A and Histone H2A type 3. |
| Immunogen: |
Synthetic peptide of Histone H2A (Acetyl Lys9) |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Protein Name | Histone H2a Type 1H2a.1Histone H2a/Ptl |
| Database Links | Reactome: R-HSA-3214815Reactome: R-HSA-3214847Reactome: R-HSA-3214858Reactome: R-HSA-5689603Reactome: R-HSA-5689880Reactome: R-HSA-5689901Reactome: R-HSA-9609690Reactome: R-HSA-9610379 |
| Cellular Localisation | NucleusChromosome |
| Alternative Antibody Names | Anti-Histone H2a Type 1 antibodyAnti-H2a.1 antibodyAnti-Histone H2a/Ptl antibodyAnti-H2AC11 antibodyAnti-H2AFP antibodyAnti-HIST1H2AG.H2AC13 antibodyAnti-H2AFC antibodyAnti-HIST1H2AI.H2AC15 antibodyAnti-H2AFD antibodyAnti-HIST1H2AK.H2AC16 antibodyAnti-H2AFI antibodyAnti-HIST1H2AL.H2AC17 antibodyAnti-H2AFN antibodyAnti-HIST1H2AM antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
