• Western blot analysis of lysates from COS7 cells, treated with TSA 400nM 24h, using Histone H1 (Acetyl-Lys25) Antibody. The lane on the right is blocked with the synthesized peptide.
  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Histone H1 (Acetyl-Lys25) Antibody. The picture on the right is blocked with the synthesized peptide.

Anti-Acetyl-H1-8-K25 antibody (100-180) (STJ90116)


Current Stock:
Host: Rabbit
Applications: WB, IHC-P, IF-P, ELISA
Reactivity: Human, Monkey
Short Description: Rabbit polyclonal antibody anti-Acetyl-Histone H1.8-K25 (100-180) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: H1-8
Gene ID: 132243
Uniprot ID: H18_HUMAN
Immunogen Region: 100-180
Specificity: Acetyl-H1-8-K25 polyclonal antibody (Histone H1.8) binds to endogenous Histone H1.8 at the amino acid region 100-180.
Immunogen: The antiserum was produced against synthesized peptide derived from human Histone H1 around the acetylated site of Lys25 at amino acid range 131-180
Function May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Protein Name Histone H1.8
Histone H1oo
Oocyte-Specific Histone H1
Oocyte-Specific Linker Histone H1
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Histone H1.8 antibody
Anti-Histone H1oo antibody
Anti-Oocyte-Specific Histone H1 antibody
Anti-Oocyte-Specific Linker Histone H1 antibody
Anti-Osh1 antibody
Anti-H1-8 antibody
Anti-H1FOO antibody
Anti-H1OO antibody
Anti-OSH1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance