• Western blot analysis of extracts from rat kidney, using Aladin Polyclonal Antibody.. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-AAAS antibody (360-440 aa, C-terminal) (STJ96407)

SKU:
STJ96407

Current Stock:
Host: Rabbit
Applications: WB, ELISA
Reactivity: Human, Rat
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Rabbit polyclonal antibody Anti-Aladin (360-440 aa, C-terminal) is suitable for use in Western Blot and ELISA.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Concentration: 1 mg/ml
Dilution Range: WB 1:500-1:2000
ELISA 1:40000
Storage Instruction: Store at-20°C, and avoid repeat freeze-thaw cycles.
Gene Symbol: AAAS
Gene ID: 8086
Uniprot ID: AAAS_HUMAN
Immunogen Region: 360-440 aa, C-terminal
Specificity: Aladin polyclonal antibody detects endogenous levels of Aladin protein.
Immunogen: Synthesized peptide derived from human Aladin
Function Plays a role in the normal development of the peripheral and central nervous system. Required for the correct localization of aurora kinase AURKA and the microtubule minus end-binding protein NUMA1 as well as a subset of AURKA targets which ensures proper spindle formation and timely chromosome alignment.
Protein Name Aladin
Adracalin
Database Links Reactome: R-HSA-1169408
Reactome: R-HSA-159227
Reactome: R-HSA-159230
Reactome: R-HSA-159231
Reactome: R-HSA-159236
Reactome: R-HSA-165054
Reactome: R-HSA-168271
Reactome: R-HSA-168276
Reactome: R-HSA-168325
Reactome: R-HSA-168333
Reactome: R-HSA-170822
Reactome: R-HSA-180746
Reactome: R-HSA-180910
Reactome: R-HSA-191859
Reactome: R-HSA-3108214
Reactome: R-HSA-3232142
Reactome: R-HSA-3301854
Reactome: R-HSA-3371453
Reactome: R-HSA-4085377
Reactome: R-HSA-4551638
Reactome: R-HSA-4570464
Reactome: R-HSA-4615885
Reactome: R-HSA-5578749
Reactome: R-HSA-5619107
Reactome: R-HSA-6784531
Reactome: R-HSA-9609690
Reactome: R-HSA-9610379
Cellular Localisation Nucleus
Nuclear Pore Complex
Cytoplasm
Cytoskeleton
Spindle Pole
Nucleus Envelope
In Metaphase Cells Localizes Within The Spindle With Some Accumulation Around Spindle Poles
With The Highest Concentration Between The Centrosome And Metaphase Plate
The Localization To The Spindle Is Microtubule-Mediated
Alternative Antibody Names Anti-Aladin antibody
Anti-Adracalin antibody
Anti-AAAS antibody
Anti-ADRACALA antibody
Anti-GL003 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance