• Anti-14-3-3 sigma/Stratifin, Biotinylated Antibody (STJ73293)
  • Anti-14-3-3 sigma/Stratifin, Biotinylated Antibody (STJ73293)

Anti-14-3-3 sigma/Stratifin, Biotinylated Antibody (STJ73293)

SKU:
STJ73293

Current Stock:
Host: Goat
Applications: Pep-ELISA, WB, IHC
Reactivity: Human, Mouse, Rat, Dog, Pig
Short Description: Goat polyclonal anti-14-3-3 sigma/Stratifin, Biotinylated antibody is suitable for use in ELISA, Western Blot and Immunohistochemistry.
Note: FOR RESEARCH USE ONLY (RUO).
Clonality: Polyclonal
Conjugation: Unconjugated
Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at-20°C. Minimize freezing and thawing.
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Storage Instruction: Store at-20°C and avoid freeze-thaw cycles.
Concentration: 0.5mg/mL
Isotype: IgG
Dilution Range: WB-0.1-0.3µg/ml
ELISA-antibody detection limit dilution 1:16000.
Uniprot ID: 1433S_MOUSE
Gene ID: 55948
Gene Symbol: Sfn
Immunogen Region: internal region
Immunogen Sequence: CDLHTLSEDSYKDST.
Accession Number: NP_006133.1
Post Translational Modifications Ubiquitinated. Ubiquitination by RFFL induces proteasomal degradation and indirectly regulates p53/TP53 activation.
Function Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
Protein Name 14-3-3 Protein Sigma
Stratifin
Database Links Reactome: R-MMU-111447
Reactome: -MMU-5625740
Reactome: -MMU-5628897
Reactome: -MMU-6804114
Reactome: -MMU-75035
Reactome: -MMU-9614399
Cellular Localisation Cytoplasm
Nucleus
Secreted
May Be Secreted By A Non-Classical Secretory Pathway
Alternative Antibody Names Anti-14-3-3 Protein Sigma antibody
Anti-Stratifin antibody
Anti-Sfn antibody
Anti-Mkrn3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance