• Western blot analysis of lysates from NIH/3T3 cells, using 14-3-3 beta/zeta Antibody. The lane on the right is blocked with the synthesized peptide.

Anti-14-3-3 Beta/Zeta antibody (120-200) (STJ91368)

SKU:
STJ91368

Current Stock:
Host: Rabbit
Applications: WB, IHC-P, IF-P, ELISA
Reactivity: Human, Mouse, Rat
Note: FOR RESEARCH USE ONLY (RUO).
Short Description: Rabbit polyclonal antibody anti-14-3-3 protein zeta/delta and 14-3-3 protein beta/alpha (120-200) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit anti-serum by affinity-chromatography.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: YWHAZ
YWHAB
Gene ID: 7534
7529
Uniprot ID: 1433Z_HUMAN
1433B_HUMAN
Immunogen Region: 120-200
Specificity: 14-3-3 Beta/Zeta polyclonal antibody (14-3-3 protein zeta/delta and 14-3-3 protein beta/alpha) binds to endogenous 14-3-3 protein zeta/delta and 14-3-3 protein beta/alpha at the amino acid region 120-200.
Immunogen: The antiserum was produced against synthesized peptide derived from human YWHAZ at amino acid range 151-200
Function Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation. In neurons, regulates spine maturation through the modulation of ARHGEF7 activity.
Protein Name 14-3-3 Protein Zeta/Delta
Protein Kinase C Inhibitor Protein 1
Kcip-1
Database Links Reactome: R-HSA-111447
Reactome: R-HSA-1445148
Reactome: R-HSA-3769402
Reactome: R-HSA-392517
Reactome: R-HSA-430116
Reactome: R-HSA-450604
Reactome: R-HSA-512988
Reactome: R-HSA-5625740
Reactome: R-HSA-5628897
Reactome: R-HSA-75035
Reactome: R-HSA-9013700
Reactome: R-HSA-9604323
Reactome: R-HSA-9614399
Cellular Localisation Cytoplasm
Melanosome
Located To Stage I To Stage Iv Melanosomes
Alternative Antibody Names Anti-14-3-3 Protein Zeta/Delta antibody
Anti-Protein Kinase C Inhibitor Protein 1 antibody
Anti-Kcip-1 antibody
Anti-YWHAZ antibody

Information sourced from Uniprot.org

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